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STAR is a distance based tool for rapid and accurate determination of HIV-1 and HBV subtype according to an underlying statistical model.
STAR assigns HIV-1 subtypes using either nucleotide or protein sequences of the protease (PR) and reverse transcriptase (RT) genes, and HBV subtypes using nucleotide sequences of any genomic region. Click here for information on the subtyping process
Submit Pol, surface coding region or entire genome sequence.
STAR is developed and maintained by Richard E. Myers and Arshad Khan
References
Myers, RE, Clarke, C., Khan, A., Kellam, P., Tedder, R. (2006). Genotyping Hepatitis B Virus from whole and sub-genomic fragments using position specific scoring matrices in STAR-HBV. J. Gen Virol. (in press).
Gifford R, de Oliveira, T, Rambaut A, Myers RE, Gale CV, Dunn D, Shafer R, Vandamme A, Kellam P, and D. Pillay (2006) Assessment of Automated Genotyping Protocols as Tools for Surveillance of HIV-1 Genetic Diversity. AIDS (in press)
Myers RE, Gale CV, Harrison A, Takeuchi Y, Kellam P. (2005) A statistical model for HIV-1 sequence classification using the subtype analyser (STAR). Bioinformatics, 21:3535-3540.
Gale CV, Myers RE, Tedder, RS, Williams IG, Kellam P. (2004) Development of a novel human immunodeficiency virus type 1 subtyping tool, Subtype Analyser (STAR): Analysis of subtype distribution in London. AIDS Res. Hum. Retroviruses, 20:457-464.
This page last modified
28 April 2006
by Robert Gifford
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